出生于长岛的白人青年尤金·马东（拉尔夫·马奇奥 Ralph Macchio 饰）在古典吉他的演奏上拥有极高的天分，但是他如此热爱蓝调布鲁斯，尤其对传奇黑人布鲁斯歌手罗伯特·约翰逊（蒂姆·罗斯 Tim Russ 饰）着迷不已。据说约翰逊生前曾录下30首歌曲，但只有前29首流传于世。为了找到那首失落的歌曲，他辗转找到约翰逊当年的搭档——前布鲁斯乐队“盲狗福尔敦”成员威利·布朗（Joe Seneca 饰），甚至不惜以勤杂工的身份进入布朗所在的养老院。通过音乐，一老一少拉近彼此距离，威利则瞅准时机让马东带他离开养老院。　　他们即将启程前往盲狗福尔敦的发源地密西西比州，寻找曾与音乐家们做过交易的魔鬼，寻找那首失落的传奇之歌……

The main character is Dr. Max Holst, a successful neurosurgeon. One day an intense little man named Steinmetz shows up, who has the real ability to create objects out of thin air, using only his mind. As no one believes him at first, he is held at a ward for mental patients, but manifests the key to his door and escapes. As he has a special interest in Dr. Holst, Steinmetz subsequently invites Holst to his large mansion, which is full of expensive paintings and sculptures, and proves to him that he can in fact materialise objects. Steinmetz’s abilities are evolving by leaps and bounds, and is progressing from being able to create objects only to being able to create living things. His ultimate ambition is to be able to create a human being. He tells Dr. Holst that if he will only perform a certain brain operation on him, Steinmetz will become able to attain his goal. He’s got all the necessary equipment set up in his basement. Dr. Holst, however, is too spooked by the whole thing to agree to this mad scheme, and refuses. Steinmetz then sets about manipulating Holst’s life, to pressure him into performing the operation. By then Steinmetz has become able to create a temporary human being, and in the hope that he can perhaps make his own creation perform the operation, he manifests a doppelganger of Dr. Holst. This double proceeds to take over Dr. Holst’s life, creating chaos for him professionally and personally. And then Dr. Holst starts fighting back. The ending has the dual virtue of being both unexpected and satisfying.